Case Study 2

Complicated Urinary Tract Infection (UTI) in Secondary Care

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Background:

A 32-year-old woman is admitted to the hospital with flank pain, fever, and nausea. She is 18 weeks pregnant. She reports dysuria and urinary frequency for 3 days before admission. She has no known allergies. Past medical history includes one episode of pyelonephritis two years ago (non-pregnant).

 
Observations & Examination Findings:

  • Temperature: 39.0°C
  • Heart rate: 105 bpm
  • Blood pressure: 110/70 mmHg
  • Respiratory rate: 18 breaths/min
  • CVA tenderness: left-sided

Investigations:

  • Urinalysis: positive nitrites, leukocyte esterase
  • Blood tests: WCC 15.8 × 10⁹/L, CRP 112 mg/L
  • Blood cultures: pending
  • Urine culture: pending

 


 

Learning prompts for the student:

Learning prompts for the student:

1. What is the likely diagnosis ,differential diagnosis and immediate priorities?
2. What investigations would you make before/alongside antibiotics?
3. Why is the infection classified as “complicated” in this context?
4. Antibiotic selection: Which empiric IV antibiotic regimen is safe in pregnancy and recommended in national/local guidelines for pyelonephritis? What should be avoided?
5. What supportive management would you initiate?
6. What would be your follow up and preventative measures with recurrent UTIs?
7. Counselling: What information should be provided to the patient regarding antibiotic use in pregnancy and potential risks to the foetus?

 


 

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